If genitourinary complaints are reported, urinalysis and urine. Pathophysiology and treatment of spinal tuberculosis. In 1779, percivall pott, for whom the disease is named, presented the classic description o. Tuberculosis of spine presentation and treatment bone. The kyphotic deformity is caused by collapse in the anterior spine. Currently, the term potts diseasepotts spine describes tuberculous infection of the. Advanced imaging techniques such as magnetic resonance imaging mri make the early diagnosis of spinal tb easier and a considerable. Cervical spine tuberculosis is a less common presentation but is potentially more serious because severe neurologic complications are more. Progressive bone destruction leads to vertebral collapse and kyphosis. Images show the thoracic spine before and after an infusion of intravenous gadolinium. Meningeal tuberculosis occurs when tuberculosis travels through the bloodstream to the membranes surrounding the brain and spinal cord, called the meninges. If vertebral pott disease or brain involvement is suspected, ct or mri is necessary. Tuberculosis infection of the second cervical spine is a very rare case and has an incidence rate of only 1 in 100,000.
It is associated with significant morbidity and can lead to severe functional impairment. Three mri parameters have been found to be strongly suggestive of spinal tuberculosis. The spinal column is involved in less than 1% of all cases of tuberculosis tb. Pott disease, also known as tuberculous spondylitis, is a classic presentation of extrapulmonary tuberculosis tb. It accounts for approximately half of all cases of musculoskeletal tuberculosis. Pott disease tuberculous tb spondylitis clinical presentation. Spinal tap carries some risk of herniation of the medulla in any instance when intracranial pressure icp is increased eg, tbm, but if meningitis. Until the introduction of effective anti tuberculosis drugs, treat ment for tuberculosis of the spine required enforced recumbency, im mobilization and hospitalization for several years, preferably in special. Although tb rates are decreasing in the united states, the disease is becoming more. Spinal tuberculosis is a destructive form of tuberculosis. Although tb rates are decreasing in the united states, the disease is.
Spinal tb is a very dangerous type of skeletal tb as it can be associated with neurologic deficit due to compression of adjacent neural structures and significant spinal deformity. Cervical spine tuberculosis is a less common presentation but is potentially more serious because severe neurologic complications are more likely. Consequently, further evaluation is necessary with ct scanning or mri. Lesions in the thoracic spine are more likely to lead to kyphosis than those in the lumbar spine. Tuberculosis of spine standard treatment guidelines. The tuberculin skin test also called the mantoux tuberculin test can tell if you have this form of. Miliary tuberculosis exhibits diffuse nodules at different locations in the body. Mri is the neuroimaging of choice for spinal tuberculosis. Pott disease tuberculous tb spondylitis medscape reference. Other granulomatous processes, particularly brucellosis. Pott disease, also known as tuberculous spondylitis, is one of the oldest demonstrated diseases of humankind, having been documented in spinal remains from the iron age in europe and in ancient mummies from egypt and the pacific coast of south america. Tuberculosis tb see the image below, a multisystemic disease with myriad presentations and manifestations, is the most common cause of infectious diseaserelated mortality worldwide.
Which testing is needed when vertebral pott disease or brain. What is the pathophysiology of the spinal tuberculosis. Although tb rates are decreasing in the united states, the disease is becoming more common in many parts of the world. Reactivated tb bacteria usually infiltrate the upper lobes of the lungs. The average prevalence of all forms of tuberculosis in india is estimated to be 5 per thousand skeletal system involvement occurs in 1% to 3% of the patients and up to 50% of these affected patients have tb of the spine differential diagnosis tumours of spine. Mri of a 31yearold man with tuberculosis of the spine. Pdf management of tuberculous infection of the spine. Vertebral collapse of a lesser magnitude is not considered an indication for surgery because. The mantoux skin test also known as a tuberculin skin test tst or ppd test. Pott disease tuberculous spondylitis medical article with mri picture, emedicine. Pott disease is tuberculosis of the spine, usually due to haematogenous spread from other sites. No response to medical therapy continuing progression of kyphosis or instability. Tuberculosis of spine is the most common site of skeletal tuberculosis accounts for 50 percent of the cases and may cause neural symptoms as well. Other infectious afflictions of spine like brucella, pyogenic.
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